High Mail queue /Mail flow issue -
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1. Check the queue & observe - Identify what kind of mails are stuck ( there are chances of spam / autogenerated or application relaying mails causing issue) .
2. Check any Services are stopped ? - Ensure all necessary services started
3. Check in Event Viewer for any error.
4. Ensure no time difference between Exchnage,AD servers.
5. Check any other server Eg: Mailbox , having issues ? or if any specific location server or network bandwidth or port (Firewall level)issues ?
6. Check Resource utilization, Server's Uptime & reboot if very high uptime or higher resource usage
7. Verify all database status, mount if any Database store dismounted or troubleshoot verifying transaction log files,disk space etc ,Use eseutil - recovery or repair methods if issues during mounting.
8. Check by stopping antivirus or if any Mail security clients.
9. Coordinate with ISP,Mail secuirty products / Network level if external mailflow issues
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